Addressing social determinants of health in patients with cardiovascular-kidney-metabolic syndrome: What works, what does not?

To progress, aligning guideline-driven CKM care with multilevel SDoH interventions that are widely available, sustainable, and community-informed is critical. Health systems can begin by standardizing SDoH screening using validated tools, integrating polysocial risk metrics into CKM risk stratification, and building interdisciplinary teams that include social and community health workers and patient navigators empowered to connect patients with community resources. Payers and policymakers can support food-is-medicine, transportation, and digital-access programs as core CKM services, especially in historically redlined or other structurally disadvantaged communities. Ultimately, integration of CKM treatment with SDoH assessment will help fulfill the need to apply evidence-based medicine across all populations regardless of race/ethnicity, sex/gender, geography, socioeconomic status, ability, or disability.