Back to search results

Navigation and care coordination in breast cancer: Early findings from a phase I clinical trial

Ofori-Darko A, Walker M, Burnette UJ, McClelland S
Am J Clin Oncol

OBJECTIVE: To examine the impact of patient navigation on care coordination, health care access, appointment adherence, psychosocial outcomes, and equity among patients with breast cancer enrolled in the Navigator-Assisted Hypofractionation (NAVAH) trial. 

METHODS: This prospective comparative analysis used pre- and postradiotherapy (RT) survey data from an ongoing multicenter phase I trial. The pre-RT cohort included 44 patients; post-RT analyses compared 14 patients who electively received navigation with 13 who did not. The cohort was predominantly low-income, with 89% reporting annual household income below $50,000. 

RESULTS: At baseline, the mean pre-RT composite score was 31.1, with transportation challenges and mixed perceptions of equitable care commonly reported. Post-RT, navigated patients reported more favorable accessibility, accommodation, and acceptability scores than nonnavigated patients, while affordability scores were similar. Complete appointment attendance was 92% with navigation versus 83% without navigation. 

CONCLUSIONS: Patient navigation was associated with more favorable health care access experiences, though adherence differences were not statistically significant.

Ofori-Darko A, Walker M, Burnette UJ, McClelland S. Navigation and care coordination in breast cancer: early findings from a phase I clinical trial. Am J Clin Oncol. 2026. DOI:10.1097/coc.0000000000001357. PMID: 42549831

View the Resource Opens in a new window
Publication year
Resource type
Peer Reviewed Research
Outcomes
Social Needs/ SDH
Health & Health Behaviors
Population
Complex Patients
Social Determinant of Health
Transportation
Study design
Other Study Design