Back to Evidence & Resource Library

Pragmatic clinical trial to improve patient experience among adults during transitions from hospital to home: the PArTNER study

S.L LaBedz, V. Prieto-Centurion, A. Mutso, S. Basu, N.E. Bracken, E.A. Calhoun, R.J. DiDomenico, M. Joo, A.S. Pickard, B. Pittendrigh, M.V. Williams, S. Illendula, J.A. Krishnan
J Gen Intern Med

Introduction: Minority-serving hospitals (MSHs) need evidence-based strategies tailored to the populations they serve to improve patient-centered outcomes after hospitalization. Methods: We conducted a pragmatic randomized clinical trial (RCT) from October 2014 to January 2017 at a MSH comparing the effectiveness of a stakeholder-supported Navigator intervention vs. Usual care on post-hospital patient experience, outcomes, and healthcare utilization. Community health workers and peer coaches delivered the intervention which included (1) in-hospital visits to assess barriers to health/healthcare and to develop a personalized Discharge Patient Education Tool (DPET); (2) a home visit to review the DPET; and (3) telephone-based peer coaching. The co-primary outcomes were between-group comparisons of 30-day changes in Patient-Reported Outcomes Measurement Information System (PROMIS) measures of anxiety and informational support (minimum important difference is 2 to 5 units change); a p-value <0.025 was considered significant using intention-to-treat analysis. Secondary outcomes included death, ED visits, or readmissions and measures of emotional, social, and physical health at 30 and 60 days. Results: We enrolled 1029 adults hospitalized with heart failure (28%), pneumonia (22%), MI (10%), COPD (11%), or sickle cell disease (29%). Over 80% were non-Hispanic Black. Overall, there were no significant between-group differences in the 30-day change in anxiety (adjusted difference: −1.6, 97.5% CI −3.3 to 0.1, p=0.03), informational support (adjusted difference: −0.01, 97.5% CI −2.0 to 1.9, p=0.99), or any secondary outcomes. Exploratory analyses suggested the Navigator intervention improved anxiety among participants with COPD, a primary care provider, a hospitalization in the past 12 months, or higher baseline anxiety; among participants without health insurance, the intervention improved informational support (all p-values <0.05). Conclusions: In this pragmatic RCT at a MSH, the Navigator intervention did not improve post-hospital anxiety, informational support, or other outcomes compared to Usual care. Benefits observed in participant subgroups should be confirmed in future studies.

LaBedz SL, Prieto-Centurion V, Mutso A, et al. Pragmatic clinical trial to improve patient experience among adults during transitions from hospital to home: the PArTNER study [published online ahead of print, 2022 Mar 8]. J Gen Intern Med. 2022;10.1007/s11606-022-07461-0. doi:10.1007/s11606-022-07461-0 PMID: 35260961

View the Resource
Publication year
Resource type
Peer Reviewed Research
Health & Health Behaviors
Patient Experience of Care
Provider Experience of Care
Social Determinant of Health
Not Specified
Study design
Randomized Controlled Trial (RCT)