As cardio-oncology matures, its continued inattention to the social determinants of health (SDOH) represents a critical blind spot in both clinical care and health equity. Despite growing recognition of how factors like income, housing, and transportation shape cardiovascular outcomes in cancer patients, their routine integration into care remains limited. This review underscores that implementation science frameworks such as RE-AIM, PRISM, and CFIR offer structured, evidence-informed pathways to translate knowledge into practice. With scalable strategies from EHR-based screening to community health worker interventions now available, the field is well-positioned to lead. Advancing equity in cardio-oncology requires not just awareness but deliberate, systematic action rooted in implementation science.