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Social determinants of health, personalized medicine, and child maltreatment

W.G. Lane, H. Dubowitz
Pediatr Res

This review begins with a brief summary of the importance of child maltreatment as a major public health problem, given its prevalence and the substantial human and economic costs involved. The focus then shifts to consideration of personalized medicine and child maltreatment, including genetic and genomics factors, as well as the role of social determinants of health. Research on epigenetics related to child abuse and neglect is presented, followed by that pertaining to a few specific social factors, such as poverty, parental depression and substance use, and domestic (or intimate partner) violence. The review ends with a discussion of interventions to help address social determinants of health with brief descriptions of several model programs, and thoughts concerning the role of personalized medicine in addressing child maltreatment in the foreseeable future.

Lane WG, Dubowitz H. Social determinants of health, personalized medicine, and child maltreatment. Pediatr Res. 2020 Dec 7. doi: 10.1038/s41390-020-01290-9. Epub ahead of print. PMID: 33288877.

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Publication year
Resource type
Peer Reviewed Research
Children and Youth
Social Determinant of Health
Economic Security
Study design